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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Fabp4-lacZ)4Mosh
transgene insertion 4, Moshe Shani
MGI:4849449
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sor+
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0 		involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL MGI:4849465
cn2
 		Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sortm1(PDGFB)Cbet
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0 		involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL MGI:4849467
cx3
 		Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet
Tg(Fabp4-lacZ)4Mosh/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:4849469


Genotype
MGI:4849465
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sor+
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(PDGFB)Cbet mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
Pdgfbtm1Cbet mutation (0 available); any Pdgfb mutation (15 available)
Tg(Fabp4-lacZ)4Mosh mutation (1 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal blood vessel morphology ( J:166532 )
• mural cell (pericytes and vascular smooth muscle cells) densities are lower than in wild-type mice




Genotype
MGI:4849467
cn2
Allelic
Composition		 Gt(ROSA)26Sortm1(PDGFB)Cbet/Gt(ROSA)26Sortm1(PDGFB)Cbet
Pdgfbtm1Cbet/Pdgfbtm1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(PDGFB)Cbet mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
Pdgfbtm1Cbet mutation (0 available); any Pdgfb mutation (15 available)
Tg(Fabp4-lacZ)4Mosh mutation (1 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:166532 )
N
• mural cell (pericytes and vascular smooth muscle cells) densities are close to normal




Genotype
MGI:4849469
cx3
Allelic
Composition		 Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet
Tg(Fabp4-lacZ)4Mosh/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdgfbtm3.1Cbet mutation (0 available); any Pdgfb mutation (15 available)
Tg(Fabp4-lacZ)4Mosh mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal blood vessel morphology ( J:166532 )
• mural cell (pericytes and vascular smooth muscle cells) densities are lower than in wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory