All Phenotypes Dzank1<tm1a(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dzank1^{tm1a(KOMP)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4841203

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dzank1^{tm1a(KOMP)Wtsi}/Dzank1^{tm1a(KOMP)Wtsi}	involves: C57BL/6N	MGI:5912190
cx2	Dzank1^{tm1a(KOMP)Wtsi}/Ppcd1	involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * DBA/2J	MGI:5912189
cx3	Dzank1^{tm1a(KOMP)Wtsi}/Dzank1⁺ Kat14^{tm1d(KOMP)Wtsi}/Kat14⁺	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N * DBA/2J	MGI:5912196

Allelic Composition	Dzank1^{tm1a(KOMP)Wtsi}/Dzank1^{tm1a(KOMP)Wtsi}
Genetic Background	involves: C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dzank1^{tm1a(KOMP)Wtsi} mutation (1 available); any Dzank1 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:236024 )

N	• mice are viable

Allelic Composition	Dzank1^{tm1a(KOMP)Wtsi}/Ppcd1
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dzank1^{tm1a(KOMP)Wtsi} mutation (1 available); any Dzank1 mutation (43 available)
Ppcd1 mutation (1 available); any Ppcd1 mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:236024 )

• 50% of mice die prior to birth

Allelic Composition	Dzank1^{tm1a(KOMP)Wtsi}/Dzank1⁺ Kat14^{tm1d(KOMP)Wtsi}/Kat14⁺
Genetic Background	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dzank1^{tm1a(KOMP)Wtsi} mutation (1 available); any Dzank1 mutation (43 available)
Kat14^{tm1d(KOMP)Wtsi} mutation (0 available); any Kat14 mutation (73 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:236024 )

N	• unlike Ppcd1 heterozygotes, mice does not exhibit enlarged eyes at 4 to 5 months

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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