All Phenotypes Gt(ROSA)26Sor<tm1(pb)Peli> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^tm1(pb)Peli
targeted mutation 1, Pentao Liu
MGI:4840546

Summary

13 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H39Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840547
cn2	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H8Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840548
cn3	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H5Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840549
cn4	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H12Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840550
cn5	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H31Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840552
cn6	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H32Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840557
cn7	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H27Brd/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:4840558
cn8	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP3)S2Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840553
cn9	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)S1Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840555
cn10	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)S2Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840556
cn11	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)S1Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840559
cn12	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)S2Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840560
cn13	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP3)S1Brd/0	involves: 129S7/SvEvBrd * FVB	MGI:4840561

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H39Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(pb)Peli mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
TgTn(pb-sb-ATP1)H39Brd mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:166063 )

• no live-born mice are found but embryos are found at E11.5 indicating embryonic lethality

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H8Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:166063 )

• no live-born mice are found indicating embryonic lethality

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H5Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:166063 )

• fewer than expected live-born mice are found indicating embryonic lethality

neoplasm

abnormal tumor susceptibility ( J:166063 )

• survivors develop primarily solid tumors

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)H12Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:166063 )

• fewer than expected live-born mice are found indicating embryonic lethality

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H31Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:166063 )

• fewer than expected live-born mice are found indicating embryonic lethality

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H32Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily hematopoietic tumors

increased leukemia incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

increased lymphoma incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)H27Brd/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily hematopoietic tumors

increased leukemia incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

increased lymphoma incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP3)S2Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:166063 )

• no live-born mice are found indicating embryonic lethality

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)S1Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily hematopoietic tumors

increased leukemia incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

increased lymphoma incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP2)S2Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily hematopoietic tumors

increased leukemia incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

increased lymphoma incidence ( J:166063 )

• most mice develop aggressive leukemias and lymphomas

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)S1Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily solid tumors

increased carcinoma incidence ( J:166063 )

• develop various carcinomas with poor differentiation and metastasis

increased sarcoma incidence ( J:166063 )

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP1)S2Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop primarily solid tumors

increased carcinoma incidence ( J:166063 )

• develop various carcinomas with poor differentiation and metastasis

increased sarcoma incidence ( J:166063 )

Allelic Composition	Gt(ROSA)26Sor^tm1(pb)Peli/Gt(ROSA)26Sor⁺ TgTn(pb-sb-ATP3)S1Brd/0
Genetic Background	involves: 129S7/SvEvBrd * FVB

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:166063 )

neoplasm

abnormal tumor susceptibility ( J:166063 )

• develop both solid and hematopoietic tumors with many mice having both types of tumors

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