Gt(ROSA)26Sor^tm1(pb)Peli
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(pb)Peli
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Pentao Liu
• MGI ID: MGI:4840546
• Synonyms: RosaPB, Rosa-PBase
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(pb)Peli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166063
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Transposase)
• Mutation: Insertion
• Mutation details: A cassette containing a splice acceptor site followed by a PiggyBac transposase gene and polyA signal and a neo cassette were inserted into the gene via homologous recombination. (J:166284)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^tm1(pb)Peli

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:166284 Wang W, et al., Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9290-5
• All: 7 reference(s)