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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ncoa6tm3.1Jxu
targeted mutation 3.1, Jianming Xu
MGI:4837690
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ncoa6tm3.1Jxu/Ncoa6tm3.1Jxu involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:4837888
cn2
 		Ncoa6tm3Jxu/Ncoa6tm3.1Jxu
Tg(Pax6-cre,GFP)1Pgr/0 		involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:4837886
cx3
 		Ncoa6tm3.1Jxu/Ncoa6+
Tg(Cryaa-NCOA6*)AD5Cve/0 		involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:4837889


Genotype
MGI:4837888
hm1
Allelic
Composition		 Ncoa6tm3.1Jxu/Ncoa6tm3.1Jxu
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncoa6tm3.1Jxu mutation (0 available); any Ncoa6 mutation (100 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:165054 )
• lens phenotype are less severe than in Tg(Cryaa-NCOA6*)AD5Cve mice




Genotype
MGI:4837886
cn2
Allelic
Composition		 Ncoa6tm3Jxu/Ncoa6tm3.1Jxu
Tg(Pax6-cre,GFP)1Pgr/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncoa6tm3.1Jxu mutation (0 available); any Ncoa6 mutation (100 available)
Ncoa6tm3Jxu mutation (0 available); any Ncoa6 mutation (100 available)
Tg(Pax6-cre,GFP)1Pgr mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
cataract ( J:165054 )
• at P21 to 2.5 months
small lens ( J:165054 )
• lens phenotype are less severe than in Tg(Cryaa-NCOA6*)AD5Cve mice




Genotype
MGI:4837889
cx3
Allelic
Composition		 Ncoa6tm3.1Jxu/Ncoa6+
Tg(Cryaa-NCOA6*)AD5Cve/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncoa6tm3.1Jxu mutation (0 available); any Ncoa6 mutation (100 available)
Tg(Cryaa-NCOA6*)AD5Cve mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
small lens ( J:165054 )
• compared with Tg(Cryaa-NCOA6*)AD5Cve mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory