Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Paip2tm1.2Nso mutation
(0 available);
any
Paip2 mutation
(33 available)
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reproductive system
N |
• female fertility is normal
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• aberrant round structures are present in the cauda epididymides unlike in wild-type mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Paip2btm1.2Nso mutation
(0 available);
any
Paip2b mutation
(18 available)
Paip2tm1.2Nso mutation
(0 available);
any
Paip2 mutation
(33 available)
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reproductive system
N |
• female fertility is normal
• testes and seminal vesicle weights are normal
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• mice exhibit aberrant spermatozoa in the epithelia along the lumen of seminiferous tubules at stage VII compared with wild-type mice
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• chromatin condensation is abnormal unlike in wild-type sperm
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• spermatids contain spherical structures in the cytoplasm and various sized vacuoles in the nuclei unlike in wild-type spermatids
• mice exhibit defective elongated spermatids unlike in wild-type mice
• elongated spermatids are retained even at stages IX-XII unlike in wild-type mice
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• in late spermiogenesis, translation of mRNAs is inhibited unlike in wild-type cells
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• aberrant round structures are present in the cauda epididymides unlike in wild-type mice
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growth/size/body
endocrine/exocrine glands
cellular
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• mice exhibit aberrant spermatozoa in the epithelia along the lumen of seminiferous tubules at stage VII compared with wild-type mice
|
|
• chromatin condensation is abnormal unlike in wild-type sperm
|
|
• spermatids contain spherical structures in the cytoplasm and various sized vacuoles in the nuclei unlike in wild-type spermatids
• mice exhibit defective elongated spermatids unlike in wild-type mice
• elongated spermatids are retained even at stages IX-XII unlike in wild-type mice
|