About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(CAG-Brainbow2.1)Cle
targeted mutation 1, Hans Clevers
MGI:4835542
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Fgfr3em1.1Ntsu/Fgfr3+
Gt(ROSA)26Sortm1(CAG-Brainbow2.1)Cle/Gt(ROSA)26Sor+
Tg(Col11a2-cre/ERT)#Ntsu/0 		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl * C57BL/6NSlc MGI:8404486


Genotype
MGI:8404486
cn1
Allelic
Composition		 Fgfr3em1.1Ntsu/Fgfr3+
Gt(ROSA)26Sortm1(CAG-Brainbow2.1)Cle/Gt(ROSA)26Sor+
Tg(Col11a2-cre/ERT)#Ntsu/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl * C57BL/6NSlc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr3em1.1Ntsu mutation (0 available); any Fgfr3 mutation (54 available)
Gt(ROSA)26Sortm1(CAG-Brainbow2.1)Cle mutation (3 available); any Gt(ROSA)26Sor mutation (1209 available)
Tg(Col11a2-cre/ERT)#Ntsu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal long bone epiphyseal plate morphology ( J:390604 )
• mice administered tamoxifen at P20 show more variable angles of chondrocyte clonal cell stacks relative to the longitudinal axis of the growth plate cartilage suggesting that clonal progeny cells move in random directions and remain within the resting zone and do not move into the proliferative zone




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/08/2026
MGI 6.24 		The Jackson Laboratory