About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
wad
warsaw dilution
MGI:4818895
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
wad/wad C3H/W-wad MGI:4818896
ht2
wad/wad+ C3H/W-wad MGI:4818907
cx3
a/a
Tyrp1b/Tyrp1b
wad/wad+
Not Specified MGI:4818897
cx4
a/a
Tyrp1b/Tyrp1b
wad/wad
Not Specified MGI:4818908


Genotype
MGI:4818896
hm1
Allelic
Composition
wad/wad
Genetic
Background
C3H/W-wad
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• as on the nonagouti brown (a/a Tyrp1b/Tyrp1b) background, on the agouti background (A/A, Tyrp1+/Tyrp1+) of C3H/W, the coat color of homozygous mutant mice is significantly diluted, appearing pale buff with occasional, interspersed darker hairs

integument
• as on the nonagouti brown (a/a Tyrp1b/Tyrp1b) background, on the agouti background (A/A, Tyrp1+/Tyrp1+) of C3H/W, the coat color of homozygous mutant mice is significantly diluted, appearing pale buff with occasional, interspersed darker hairs




Genotype
MGI:4818907
ht2
Allelic
Composition
wad/wad+
Genetic
Background
C3H/W-wad
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
N
• Background Sensitivity: whereas mice heterozygous for wad on a nonagouti brown (a/a Tyrp1b/Tyrp1b) background exhibit obvious coat color dilution, on the agouti (A/A) background of C3H/W heterozygosity for this mutation has no apparent effect




Genotype
MGI:4818897
cx3
Allelic
Composition
a/a
Tyrp1b/Tyrp1b
wad/wad+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Tyrp1b mutation (29 available); any Tyrp1 mutation (162 available)
wad mutation (0 available); any wad mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• Background Sensitivity: whereas heterozygosity for this mutation has no apparent effect on the agouti (A/A) background of C3H/W, on this nonagouti brown background, the coat color of mice heterozygous for wad is obviously diluted--the shade of milk chocolate versus the dark brown of wild-type animals--with occasional, interspersed darker hairs

integument
• Background Sensitivity: whereas heterozygosity for this mutation has no apparent effect on the agouti (A/A) background of C3H/W, on this nonagouti brown background, the coat color of mice heterozygous for wad is obviously diluted--the shade of milk chocolate versus the dark brown of wild-type animals--with occasional, interspersed darker hairs




Genotype
MGI:4818908
cx4
Allelic
Composition
a/a
Tyrp1b/Tyrp1b
wad/wad
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Tyrp1b mutation (29 available); any Tyrp1 mutation (162 available)
wad mutation (0 available); any wad mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• on this background, as on the agouti background of C3H/W, the coat color of mice homozygous for this mutation is significantly diluted, appearing pale buff with occasional, interspersed darker hairs

integument
• on this background, as on the agouti background of C3H/W, the coat color of mice homozygous for this mutation is significantly diluted, appearing pale buff with occasional, interspersed darker hairs





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory