All Phenotypes Pcsk1n<tm1Jep> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pcsk1n^tm1Jep
targeted mutation 1, John E Pintar
MGI:4459814

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pcsk1n^tm1Jep/Pcsk1n^tm1Jep	Not Specified	MGI:4459815

Allelic Composition	Pcsk1n^tm1Jep/Pcsk1n^tm1Jep
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcsk1n^tm1Jep mutation (1 available); any Pcsk1n mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body weight ( J:161415 )

• male mice weight less at 7, 10-13, and 15-20 weeks of age

• however, no weight differences for female

behavior/neurological

• decreased horizontal activity, number of total movements, number of rearing movements and number of stereotypic movements

abnormal locomotor activation ( J:161415 )

• decreased horizontal activity and number of total movements

decreased vertical activity ( J:161415 )

• decrease number of rearing movements

decreased stereotypic behavior ( J:161415 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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