Analysis Tools
mortality/aging
|
• all mice die before 2 months of age and median survival is 31 days
|
cardiovascular system
|
• at 4 weeks, mice exhibit increased end-diastolic and end-systolic diameters compared with wild-type mice
|
|
• in the left and right ventricular wall
|
|
• in the ventricular wall at 3 weeks
|
|
• at 3 weeks, mice exhibit loss of ventricular function unlike wild-type mice
• at 4 weeks, fractional shortening is reduced in the ventricle compared with wild-type mice
|
|
• increased in width
|
muscle
|
• at 3 weeks, mice exhibit loss of ventricular function unlike wild-type mice
• at 4 weeks, fractional shortening is reduced in the ventricle compared with wild-type mice
|
growth/size/body
