Analysis Tools
behavior/neurological
|
• mutant mice had enhanced social interest even in a familiar mice in a social novelty test
• mutant mice had significantly prolonged total interaction in a resident-intruder test
• olfactory acuity, exploratory activity level, locomotor activity and anxiety level of the mutant mice were normal
|
nervous system
|
• decreased spine density on apical dendrites, but not on basal dendrites, of the hippocampal CA1 region
|
|
• hippocampal neurons did not complete activity-dependent phosphorylation of CREB in some hippocampal-dependent behaviors
|
