All Phenotypes Lrp5<tm1Mawa> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lrp5^tm1Mawa
targeted mutation 1, Matthew Warman
MGI:4453217

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Lrp5^tm1Mawa/Lrp5⁺	involves: 129S1/Sv * 129X1/SvJ	MGI:5014222
cn2	Lrp5^tm1Mawa/Lrp5⁺ Tg(Dmp1-cre)1Jqfe/0	involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ * FVB/N	MGI:5014225
cn3	Lrp5^tm1Mawa/Lrp5⁺ Tg(Vil1-cre)997Gum/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	MGI:5014229
cn4	Lrp5^tm1Mawa/Lrp5⁺ Tg(Prrx1-cre)1Cjt/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL	MGI:5014230

Allelic Composition	Lrp5^tm1Mawa/Lrp5⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm1Mawa mutation (1 available); any Lrp5 mutation (81 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:172746 )

N	• normal bone mass

Allelic Composition	Lrp5^tm1Mawa/Lrp5⁺ Tg(Dmp1-cre)1Jqfe/0
Genetic Background	involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm1Mawa mutation (1 available); any Lrp5 mutation (81 available)
Tg(Dmp1-cre)1Jqfe mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mass ( J:172746 )

Allelic Composition	Lrp5^tm1Mawa/Lrp5⁺ Tg(Vil1-cre)997Gum/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm1Mawa mutation (1 available); any Lrp5 mutation (81 available)
Tg(Vil1-cre)997Gum mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:172746 )

N	• normal bone mass

Allelic Composition	Lrp5^tm1Mawa/Lrp5⁺ Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm1Mawa mutation (1 available); any Lrp5 mutation (81 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mass ( J:172746 )

• in the limbs but not in the spine

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23