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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ascl1tm1.1(cre/ERT2)Jejo
targeted mutation 1.1, Jane Johnson
MGI:4452601
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ascl1tm1.1(cre/ERT2)Jejo/Ascl1tm1.1(cre/ERT2)Jejo involves: 129S6/SvEvTac * C57BL/6 * ICR MGI:5298097
ht2
 		Ascl1tm1.1(cre/ERT2)Jejo/Ascl1+ involves: 129S6/SvEvTac MGI:5298095


Genotype
MGI:5298097
hm1
Allelic
Composition		 Ascl1tm1.1(cre/ERT2)Jejo/Ascl1tm1.1(cre/ERT2)Jejo
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl1tm1.1(cre/ERT2)Jejo mutation (1 available); any Ascl1 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:178291 )
• mice die within hours of birth due to CNS and PNS disruptions in neural development

nervous system
abnormal nervous system development ( J:178291 )
• mice die within hours of birth due to CNS and PNS disruptions in neural development




Genotype
MGI:5298095
ht2
Allelic
Composition		 Ascl1tm1.1(cre/ERT2)Jejo/Ascl1+
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl1tm1.1(cre/ERT2)Jejo mutation (1 available); any Ascl1 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory