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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il25tm1Cdon
targeted mutation 1, Chen Dong
MGI:4442364
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Il25tm1Cdon/Il25tm1Cdon
Tg(Vil1-cre)997Gum/0 		involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL MGI:5767208


Genotype
MGI:5767208
cn1
Allelic
Composition		 Il25tm1Cdon/Il25tm1Cdon
Tg(Vil1-cre)997Gum/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il25tm1Cdon mutation (0 available); any Il25 mutation (17 available)
Tg(Vil1-cre)997Gum mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal colon morphology ( J:229778 )
• reduced DSS-induced colon shortening compared with wild-type mice
decreased susceptibility to induced colitis ( J:229778 )
• DSS-treated mice exhibit reduced weight loss, inflammation and colon length shortening compared with wild-type mice

growth/size/body
decreased susceptibility to weight loss ( J:229778 )
• in DSS-treated mice

immune system
decreased susceptibility to induced colitis ( J:229778 )
• DSS-treated mice exhibit reduced weight loss, inflammation and colon length shortening compared with wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory