Phenotypes associated with this allele

• Allele Symbol: Cbx6^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4441849
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cbx6^tm1a(EUCOMM)Wtsi/Cbx6^tm1a(EUCOMM)Wtsi	C57BL/6N-Cbx6^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5608448

Genotype
MGI:5608448

hm1

• Allelic Composition: Cbx6^{tm1a(EUCOMM)Wtsi}/Cbx6^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Cbx6^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0445_7_A03

Data Sources

IMPC Data for Cbx6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - WTSI

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

abnormal liver vasculature morphology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

embryo

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

abnormal Mullerian duct topology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal bile duct morphology ( J:239583 )

DMDD

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - WTSI

decreased body weight ( J:175295 )

IMPC - WTSI

heterochrony ( J:239583 )

DMDD

hematopoietic system

decreased mean platelet volume ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

♀

IMPC - WTSI

increased blood urea nitrogen level ( J:211773 )

IMPC - WTSI

decreased circulating glucose level ( J:211773 )

♂

IMPC - WTSI

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - WTSI

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - WTSI

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - WTSI

increased circulating sodium level ( J:211773 )

IMPC - WTSI

increased circulating amylase level ( J:211773 )

♀

IMPC - WTSI

increased circulating chloride level ( J:211773 )

IMPC - WTSI

immune system

blood in lymph vessels ( J:239583 )

DMDD

limbs/digits/tail

abnormal tibia morphology ( J:211773 )

♂

IMPC - WTSI

liver/biliary system

abnormal liver vasculature morphology ( J:239583 )

DMDD

abnormal bile duct morphology ( J:239583 )

DMDD

muscle

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

nervous system

absent hypoglossal nerve ( J:239583 )

DMDD

respiratory system

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

skeleton

abnormal tibia morphology ( J:211773 )

♂

IMPC - WTSI

increased bone mineral content ( J:211773 )

♂

IMPC - WTSI