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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lgi4tm1.1Jrb
targeted mutation 1.1, John R Bermingham Jr
MGI:4441311
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
H2az2Tg(Wnt1-cre)11Rth/H2az2+ 		involves: 129S4/SvJaeSor * C57BL/6J * CBA/J MGI:4441318
cn2
 		Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
Tg(Dhh-cre)1Mejr/0 		involves: 129S4/SvJaeSor * FVB/N MGI:4441321


Genotype
MGI:4441318
cn1
Allelic
Composition		 Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Lgi4tm1.1Jrb mutation (0 available); any Lgi4 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
demyelination ( J:158973 )
• in the sciatic nerve at P12 similar to Lgi4clp homozygotes




Genotype
MGI:4441321
cn2
Allelic
Composition		 Lgi4tm1.1Jrb/Lgi4tm1.1Jrb
Tg(Dhh-cre)1Mejr/0
Genetic
Background		 involves: 129S4/SvJaeSor * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lgi4tm1.1Jrb mutation (0 available); any Lgi4 mutation (32 available)
Tg(Dhh-cre)1Mejr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
demyelination ( J:158973 )
• in the sciatic nerve at P12 similar to Lgi4clp homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory