All Phenotypes Prox1<tm5(GFP/cre)Gco> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prox1^{tm5(GFP/cre)Gco}
targeted mutation 5, Guillermo Oliver
MGI:4441289

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Prox1^{tm5(GFP/cre)Gco}/Prox1⁺	involves: 129S1/Sv * NMRI	MGI:4441389
ht2	Prox1^tm1Gco/Prox1^{tm5(GFP/cre)Gco}	involves: 129S1/Sv * 129X1/SvJ * NMRI	MGI:4441390

Allelic Composition	Prox1^{tm5(GFP/cre)Gco}/Prox1⁺
Genetic Background	involves: 129S1/Sv * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1^{tm5(GFP/cre)Gco} mutation (0 available); any Prox1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:158959 )

• exhibited on this background

• Background Sensitivity: on all other backgrounds tested (no data provided), lethality is nearly 100%

Allelic Composition	Prox1^tm1Gco/Prox1^{tm5(GFP/cre)Gco}
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prox1^tm1Gco mutation (0 available); any Prox1 mutation (50 available)
Prox1^{tm5(GFP/cre)Gco} mutation (0 available); any Prox1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased lymphatic vessel endothelial cell number ( J:158959 )

• only a few scattered lymphatic endothelial cells (LECs) are found at E11.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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