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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myl1-cre)1Sjl
transgene insertion 1, Sejin Lee
MGI:4438603
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Acvr2btm1.1Zuk/Acvr2btm1.1Zuk
Tg(Myl1-cre)1Sjl/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL/J MGI:5441733
cn2
 		Gdf11tm1Sjl/Gdf11tm2.1Sjl
Tg(Myl1-cre)1Sjl/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * FVB * SJL/J MGI:4438605


Genotype
MGI:5441733
cn1
Allelic
Composition		 Acvr2btm1.1Zuk/Acvr2btm1.1Zuk
Tg(Myl1-cre)1Sjl/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvr2btm1.1Zuk mutation (0 available); any Acvr2b mutation (27 available)
Tg(Myl1-cre)1Sjl mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
increased skeletal muscle weight ( J:188599 )
• in the pectoralis, triceps, quadriceps and gastrocnemius




Genotype
MGI:4438605
cn2
Allelic
Composition		 Gdf11tm1Sjl/Gdf11tm2.1Sjl
Tg(Myl1-cre)1Sjl/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6N * FVB * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdf11tm1Sjl mutation (0 available); any Gdf11 mutation (11 available)
Gdf11tm2.1Sjl mutation (0 available); any Gdf11 mutation (11 available)
Tg(Myl1-cre)1Sjl mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
muscle phenotype ( J:158173 )
N
• mice exhibit normal muscle fiber number and type




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory