About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lig4tm3.1Fwa
targeted mutation 3.1, Frederick W Alt
MGI:4437900
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Lig4tm3.1Fwa/Lig4tm3.1Fwa
Tg(Cr2-cre)3Cgn/0 		Not Specified MGI:4437901


Genotype
MGI:4437901
cn1
Allelic
Composition		 Lig4tm3.1Fwa/Lig4tm3.1Fwa
Tg(Cr2-cre)3Cgn/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lig4tm3.1Fwa mutation (0 available); any Lig4 mutation (46 available)
Tg(Cr2-cre)3Cgn mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal class switch recombination ( J:157537 )
• mice exhibit similar class switch recombination defects observed in Lig4tm1Fwa Ightm2Cgn Igktm1Rsky Trp53tm1Tyj homozygotes

hematopoietic system
abnormal class switch recombination ( J:157537 )
• mice exhibit similar class switch recombination defects observed in Lig4tm1Fwa Ightm2Cgn Igktm1Rsky Trp53tm1Tyj homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory