Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gt(ROSA)26Sortm1(RARA*)Clmd targeted mutation 1, Cathy Mendelsohn MGI:4431227 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• renal hypoplasia with a 50-80% reduction in branch numbers at E14
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• 50-80% reduction in branch numbers at E14
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• severe renal hypoplasia with reduced branching at E14
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• renal agenesis at E14
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• barely begin to branch at E11
• severe renal hypoplasia with reduced branching at E14
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• smaller ureteric bud at E10.5 than in normal embryos
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• few ureteric bud branches or nephrons and severe patterning abnormalities at E14
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• at E14 the kidneys are greatly reduced in size than normal
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• few ureteric bud branches at E14
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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