Phenotypes associated with this allele

• Allele Symbol: Ppp1r3b^tm1.1Arte
• Allele Name: targeted mutation 1.1, TaconicArtemis
• Allele ID: MGI:4431078
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ppp1r3b^tm1.1Arte/Ppp1r3b^tm1.1Arte	involves: C57BL/6J * C57BL/6N	MGI:4431168
hm2	Ppp1r3b^tm1.1Arte/Ppp1r3b^tm1.1Arte	involves: C57BL/6N	MGI:5568694
ht3	Ppp1r3b^tm1.1Arte/Ppp1r3b^+	involves: C57BL/6J * C57BL/6N	MGI:4431169

Genotype
MGI:4431168

hm1

• Allelic Composition: Ppp1r3b^tm1.1Arte/Ppp1r3b^tm1.1Arte
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

transmission ratio distortion ( J:157291 )

• more female mice are produced than expected without a decrease in the number of males born

homeostasis/metabolism

decreased circulating glucose level ( J:157291 )

• in mice fasted for 36 hours

improved glucose tolerance ( J:157291 )

• without accumulation of hepatic glycogen

growth/size/body

decreased body weight ( J:157291 )

• mice fasted for 36 hours lose more weight than similarly treated wild-type mice

behavior/neurological

lethargy ( J:157291 )

• in mice fasted for 36 hours

Genotype
MGI:5568694

hm2

• Allelic Composition: Ppp1r3b^tm1.1Arte/Ppp1r3b^tm1.1Arte
• Genetic Background: involves: C57BL/6N

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:208923 )

N • mice exhibit normal blood glucose and liver glycogen levels after glucose injection

Genotype
MGI:4431169

ht3

• Allelic Composition: Ppp1r3b^tm1.1Arte/Ppp1r3b⁺
• Genetic Background: involves: C57BL/6J * C57BL/6N

homeostasis/metabolism

decreased circulating triglyceride level ( J:157291 )

• in mice fasted for 14 to 15 hours

improved glucose tolerance ( J:157291 )