Analysis Tools|
Allele Symbol Allele Name Allele ID |
Xcl1tm1Rakr targeted mutation 1, Richard A Kroczek MGI:4415308 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal immune cell composition
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• day 21 after immunization with ovalbumin
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• day 21 after immunization with ovalbumin
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 12 days after immunization in an adoptive transfer experiment, the number of T cells in the spleen, lymph nodes, lung, liver, and bone marrow are reduced compared with wild-type cells
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• fewer CD8+ T cells respond to antigen-cross presentation by CD8+ dendritic cells compared to in wild-type mice
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• 12 days after immunization in adoptive transfer experiments
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• immunized T cells produce less IFN-gamma on day 12 compared with similarly treated wild-type cells
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• 12 days after immunization in an adoptive transfer experiment, the number of T cells in the spleen, lymph nodes, lung, liver, and bone marrow are reduced compared with wild-type cells
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• fewer CD8+ T cells respond to antigen-cross presentation by CD8+ dendritic cells compared to in wild-type mice
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• 12 days after immunization in adoptive transfer experiments
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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