Phenotypes associated with this allele

• Allele Symbol: Spo11^tm1Nki
• Allele Name: targeted mutation 1, The Netherlands Cancer Institute
• Allele ID: MGI:4398954
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spo11^tm1Nki/Spo11^tm1Nki	involves: 129P2/OlaHsd	MGI:5295295

Genotype
MGI:5295295

hm1

• Allelic Composition: Spo11^tm1Nki/Spo11^tm1Nki
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal meiosis ( J:177475 )

• meiotic prophase is blocked

abnormal female meiosis ( J:177475 )

♀ • oocytes reach a zygotene-like stage with variable degrees of synapsis

abnormal male meiosis ( J:177475 )

♂ • spermatocytes reach a zygotene-like stage with variable degrees of synapsis

abnormal synaptonemal complex ( J:177475 )

• oocytes and spermatocytes reach a zygotene-like stage with variable degrees of synapsis

female infertility ( J:177475 )

♀

male infertility ( J:177475 )

♂

cellular

abnormal meiosis ( J:177475 )

• meiotic prophase is blocked

abnormal female meiosis ( J:177475 )

♀ • oocytes reach a zygotene-like stage with variable degrees of synapsis

abnormal male meiosis ( J:177475 )

♂ • spermatocytes reach a zygotene-like stage with variable degrees of synapsis

abnormal synaptonemal complex ( J:177475 )

• oocytes and spermatocytes reach a zygotene-like stage with variable degrees of synapsis