Phenotypes associated with this allele

• Allele Symbol: Dynll1^{Gt(EUCE0287d04)Hmgu}
• Allele Name: gene trap EUCE0287d04, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4368846
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dynll1^Gt(EUCE0287d04)Hmgu/Dynll1^Gt(EUCE0287d04)Hmgu	involves: 129P2/OlaHsd	MGI:5620378

Genotype
MGI:5620378

hm1

• Allelic Composition: Dynll1^{Gt(EUCE0287d04)Hmgu}/Dynll1^{Gt(EUCE0287d04)Hmgu}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

interrupted aortic arch ( J:217609 )

• in 14 of 21 mice

abnormal cardiac outflow tract development ( J:217609 )

• common trunk in 7 of 21 mice

dextrocardia ( J:217609 )

• in 17 of 21 mice

cellular

abnormal primary cilium morphology ( J:217609 )

• bulges and/or flattening of limb buds cilia

decreased embryonic cilium length ( J:217609 )

• with bulges around the base

abnormal embryonic neuroepithelium primary cilium morphology ( J:217609 )

• bulges and/or flattening

digestive/alimentary system

right-sided stomach ( J:217609 )

• in 14 of 21 mice

embryo

decreased embryonic cilium length ( J:217609 )

• with bulges around the base

abnormal embryonic neuroepithelium primary cilium morphology ( J:217609 )

• bulges and/or flattening

growth/size/body

right-sided stomach ( J:217609 )

• in 14 of 21 mice

left pulmonary isomerism ( J:217609 )

• complete in 2 of 21 mice

• partial in 8 of 21 mice

homeostasis/metabolism

edema ( J:217609 )

• in 9 of 21 mice

nervous system

abnormal embryonic neuroepithelium primary cilium morphology ( J:217609 )

• bulges and/or flattening

exencephaly ( J:217609 )

• in 21 of 21 mice

respiratory system

left pulmonary isomerism ( J:217609 )

• complete in 2 of 21 mice

• partial in 8 of 21 mice

small lung ( J:217609 )

• in 14 of 21 mice

absent lungs ( J:217609 )

• in 7 of 21 mice

vision/eye

coloboma ( J:217609 )

• in 21 of 21 mice

microphthalmia ( J:217609 )

• in 21 of 21 mice