About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Klhl18tm1a(KOMP)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4362936
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Klhl18tm1a(KOMP)Wtsi/Klhl18tm1a(KOMP)Wtsi C57BL/6N-Klhl18tm1a(KOMP)Wtsi MGI:6771564
hm2
 		Klhl18tm1a(KOMP)Wtsi/Klhl18tm1a(KOMP)Wtsi C57BL/6N-Klhl18tm1a(KOMP)Wtsi/Wtsi MGI:5631248


Genotype
MGI:6771564
hm1
Allelic
Composition		 Klhl18tm1a(KOMP)Wtsi/Klhl18tm1a(KOMP)Wtsi
Genetic
Background		 C57BL/6N-Klhl18tm1a(KOMP)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl18tm1a(KOMP)Wtsi mutation (3 available); any Klhl18 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:311444 )
• progressive increase with reduced waveform amplitudes as seen in Klhl18lowf homozygotes




Genotype
MGI:5631248
hm2
Allelic
Composition		 Klhl18tm1a(KOMP)Wtsi/Klhl18tm1a(KOMP)Wtsi
Genetic
Background		 C57BL/6N-Klhl18tm1a(KOMP)Wtsi/Wtsi
Cell Lines EPD0163_1_F06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl18tm1a(KOMP)Wtsi mutation (3 available); any Klhl18 mutation (35 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

hematopoietic system

homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory