All Phenotypes Rhbdf2<tm1a(KOMP)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rhbdf2^{tm1a(KOMP)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4362881

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rhbdf2^{tm1a(KOMP)Wtsi}/Rhbdf2^{tm1a(KOMP)Wtsi}	involves: C57BL/6N	MGI:5437488
ht2	Rhbdf2^m1Btlr/Rhbdf2^{tm1a(KOMP)Wtsi}	involves: C57BL/6J * C57BL/6N	MGI:5437489
cx3	Rhbdf1^em1Mvw/Rhbdf1^em1Mvw Rhbdf2^{tm1a(KOMP)Wtsi}/Rhbdf2^{tm1a(KOMP)Wtsi}	B6.Cg-Rhbdf1^em1Mvw Rhbdf2^{tm1a(KOMP)Wtsi}/Mvw	MGI:6449217

Allelic Composition	Rhbdf2^{tm1a(KOMP)Wtsi}/Rhbdf2^{tm1a(KOMP)Wtsi}
Genetic Background	involves: C57BL/6N
Cell Lines	EPD0208_1_D12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2^{tm1a(KOMP)Wtsi} mutation (1 available); any Rhbdf2 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased tumor necrosis factor secretion ( J:187583 )

• peritoneal macrophage exhibit impaired TLR-induced TNFalpha response

Allelic Composition	Rhbdf2^m1Btlr/Rhbdf2^{tm1a(KOMP)Wtsi}
Genetic Background	involves: C57BL/6J * C57BL/6N
Cell Lines	EPD0208_1_D12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2^m1Btlr mutation (1 available); any Rhbdf2 mutation (84 available)
Rhbdf2^{tm1a(KOMP)Wtsi} mutation (1 available); any Rhbdf2 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased tumor necrosis factor secretion ( J:187583 )

• peritoneal macrophage exhibit impaired TLR-induced TNFalpha response

Allelic Composition	Rhbdf1^em1Mvw/Rhbdf1^em1Mvw Rhbdf2^{tm1a(KOMP)Wtsi}/Rhbdf2^{tm1a(KOMP)Wtsi}
Genetic Background	B6.Cg-Rhbdf1^em1Mvw Rhbdf2^{tm1a(KOMP)Wtsi}/Mvw

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf1^em1Mvw mutation (0 available); any Rhbdf1 mutation (43 available)
Rhbdf2^{tm1a(KOMP)Wtsi} mutation (1 available); any Rhbdf2 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

waved hair ( J:291556 )

vision/eye

eyelids open at birth ( J:291556 )

cardiovascular system

cardiovascular system phenotype ( J:291556 )

N	• although double mutants for true null alleles are subviable with brain and heart defects, these mice do not have those defects

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23