Phenotypes associated with this allele
Allelic Composition |
F2rtm2Cgh/F2r+ F2rl1tm2Cgh/F2rl1+
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Genetic Background |
involves: 129S4/SvJae * C57BL/6 |
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F2rl1tm2Cgh mutation
(0 available);
any
F2rl1 mutation
(58 available)
F2rtm2Cgh mutation
(0 available);
any
F2r mutation
(23 available)
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embryo
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• 22% of embryos from double heterozygous by double null crosses have open hindbrain neuropores at 9.5 days post coitus (dpc)
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nervous system
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• 22% of embryos from double heterozygous by double null crosses have open hindbrain neuropores at 9.5 days post coitus (dpc)
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F2rl1tm2Cgh mutation
(0 available);
any
F2rl1 mutation
(58 available)
F2rtm1.1Cgh mutation
(1 available);
any
F2r mutation
(23 available)
Tg(Tek-F2r)1Cgh mutation
(0 available)
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mortality/aging
N |
• presence of the transgene recues the lethality observed in double null animals; number of embryos observed at 12.5-14.5 days post coitus is equal to number of wild-type embryos collected
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nervous system
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• transgene expression does not prevent exencephaly with about 20% embryos at 12.5-14.5 dpc
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cardiovascular system
N |
• lethality associated with midgestational cardiovascular failure is rescued
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