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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rpl22tm1.1Psam
targeted mutation 1.1, Paul S Amieux
MGI:4355967
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rpl22tm1.1Psam/Rpl22+
Slc6a3tm1(cre)Xz/Slc6a3+ 		involves: 129S1/Sv * 129X1/SvJ MGI:4355970
cn2
 		Rpl22tm1.1Psam/Rpl22+
Rpl3lem1Jmol/Rpl3lem1Jmol
Tg(Myh6-cre)1Jmk/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6NJ * C57BL/6NTac MGI:7434988
cn3
 		Rpl22tm1.1Psam/Rpl22+
Tg(Amh-cre)8815Reb/0 		involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:4355971


Genotype
MGI:4355970
cn1
Allelic
Composition		 Rpl22tm1.1Psam/Rpl22+
Slc6a3tm1(cre)Xz/Slc6a3+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpl22tm1.1Psam mutation (2 available); any Rpl22 mutation (46 available)
Slc6a3tm1(cre)Xz mutation (2 available); any Slc6a3 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:7434988
cn2
Allelic
Composition		 Rpl22tm1.1Psam/Rpl22+
Rpl3lem1Jmol/Rpl3lem1Jmol
Tg(Myh6-cre)1Jmk/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpl22tm1.1Psam mutation (2 available); any Rpl22 mutation (46 available)
Rpl3lem1Jmol mutation (1 available); any Rpl3l mutation (27 available)
Tg(Myh6-cre)1Jmk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:333030 )
N
• mice show normal distributions of ribosomes in cardiomyocytes




Genotype
MGI:4355971
cn3
Allelic
Composition		 Rpl22tm1.1Psam/Rpl22+
Tg(Amh-cre)8815Reb/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpl22tm1.1Psam mutation (2 available); any Rpl22 mutation (46 available)
Tg(Amh-cre)8815Reb mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory