Phenotypes associated with this allele

• Allele Symbol: Rev1^tm1.1Jow
• Allele Name: targeted mutation 1.1, Jiyang O-Wang
• Allele ID: MGI:4355740
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rev1^tm1.1Jow/Rev1^tm1.1Jow	involves: C57BL/6	MGI:4355743

Genotype
MGI:4355743

hm1

• Allelic Composition: Rev1^tm1.1Jow/Rev1^tm1.1Jow
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:151700 )

N • B cell development, maturation, and activation are normal

N • B cells exhibit normal sensitivity to DNA damaging agents

abnormal somatic hypermutation frequency ( J:151700 )

• the frequency of C:G transitions and A:T mutations in the Ig gene is decreased compared to in wild-type mice

hematopoietic system

abnormal somatic hypermutation frequency ( J:151700 )

• the frequency of C:G transitions and A:T mutations in the Ig gene is decreased compared to in wild-type mice