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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kars1Gt(AJ0130)Wtsi
gene trap AJ0130, Wellcome Trust Sanger Institute
MGI:4344829
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Kars1Gt(AJ0130)Wtsi/Kars1Gt(AJ0130)Wtsi involves: 129P2/OlaHsd MGI:6472857
cx2
Kars1Gt(AJ0130)Wtsi/Kars1+
Tg(MMTV-PyVT)634Mul/0
involves: 129P2/OlaHsd * FVB/N MGI:6472861


Genotype
MGI:6472857
hm1
Allelic
Composition
Kars1Gt(AJ0130)Wtsi/Kars1Gt(AJ0130)Wtsi
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kars1Gt(AJ0130)Wtsi mutation (1 available); any Kars1 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no viable homozygous embryos are observed up to E9.5




Genotype
MGI:6472861
cx2
Allelic
Composition
Kars1Gt(AJ0130)Wtsi/Kars1+
Tg(MMTV-PyVT)634Mul/0
Genetic
Background
involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kars1Gt(AJ0130)Wtsi mutation (1 available); any Kars1 mutation (33 available)
Tg(MMTV-PyVT)634Mul mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice exhibit a lower incidence of lung metastasis than control mice carrying the transgene on a wild-type background, as determined by counting metastatic lung nodules in female mice at 16 or 18 weeks of age





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory