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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mnd1Gt(RRS590)Byg
gene trap RRS590, BayGenomics
MGI:4332240
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mnd1Gt(RRS590)Byg/Mnd1Gt(RRS590)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:5577179
cx2
 		Mnd1Gt(RRS590)Byg/Mnd1Gt(RRS590)Byg
Psmc3iptm1Rdco/Psmc3iptm1Rdco 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 MGI:5577180


Genotype
MGI:5577179
hm1
Allelic
Composition		 Mnd1Gt(RRS590)Byg/Mnd1Gt(RRS590)Byg
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mnd1Gt(RRS590)Byg mutation (0 available); any Mnd1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal gametogenesis ( J:207221 )
• at 6 months of age
abnormal spermatogenesis ( J:207221 )
• lack of advanced spermatogenic cells
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases

cellular
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases




Genotype
MGI:5577180
cx2
Allelic
Composition		 Mnd1Gt(RRS590)Byg/Mnd1Gt(RRS590)Byg
Psmc3iptm1Rdco/Psmc3iptm1Rdco
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mnd1Gt(RRS590)Byg mutation (0 available); any Mnd1 mutation (12 available)
Psmc3iptm1Rdco mutation (0 available); any Psmc3ip mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases

cellular
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases
impaired double-strand DNA break repair ( J:207221 )
• defects in double-strand break repair

homeostasis/metabolism
impaired double-strand DNA break repair ( J:207221 )
• defects in double-strand break repair




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory