Phenotypes associated with this allele

• Allele Symbol: Sppl3^{Gt(OST279815)Lex}
• Allele Name: gene trap OST279815, Lexicon Genetics
• Allele ID: MGI:4261988
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sppl3^Gt(OST279815)Lex/Sppl3^Gt(OST279815)Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:5429507

Genotype
MGI:5429507

hm1

• Allelic Composition: Sppl3^{Gt(OST279815)Lex}/Sppl3^{Gt(OST279815)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:161922 )

• decreased exploratory activity

abnormal depression-related behavior ( J:161922 )

• decreased depressive-like response

increased anxiety-related response ( J:161922 )

♂ • male mutants exhibited an increased anxiety-like response during open field activity testing

growth/size/body

decreased lean body mass ( J:161922 )

decreased body weight ( J:161922 )

• decreased total tissue mass

decreased body length ( J:161922 )

postnatal growth retardation ( J:161922 )

reproductive system

reduced fertility ( J:161922 )