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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmem41bGt(OST208407)Lex
gene trap OST208407, Lexicon Genetics
MGI:4232785
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tmem41bGt(OST208407)Lex/Tmem41bGt(OST208407)Lex FVB.129S5-Tmem41bGt(OST208407)Lex MGI:6287400


Genotype
MGI:6287400
hm1
Allelic
Composition		 Tmem41bGt(OST208407)Lex/Tmem41bGt(OST208407)Lex
Genetic
Background		 FVB.129S5-Tmem41bGt(OST208407)Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem41bGt(OST208407)Lex mutation (1 available); any Tmem41b mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and placentation, complete penetrance ( J:272518 )
• homozygous mutant embryos are obtained in the expected Mendelian ratio at ~E8.5, but not at later stages

embryo
embryonic growth arrest ( J:272518 )
• embryos are developmentally arrested at around E7.5
abnormal embryo morphology ( J:272518 )
• embryos exhibit abnormal morphology at E8.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory