All Phenotypes Ptbp2<Gt(NPX210)Byg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptbp2^{Gt(NPX210)Byg}
gene trap NPX210, BayGenomics
MGI:4124189

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptbp2^{Gt(NPX210)Byg}/Ptbp2^{Gt(NPX210)Byg}	involves: 129P2/OlaHsd	MGI:5431216

Allelic Composition	Ptbp2^{Gt(NPX210)Byg}/Ptbp2^{Gt(NPX210)Byg}
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptbp2^{Gt(NPX210)Byg} mutation (0 available); any Ptbp2 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality ( J:185949 )

nervous system

abnormal neuron differentiation ( J:185949 )

• abnormal neural stem cell polarity

premature neuronal precursor differentiation ( J:185949 )

• premature neurogenesis

abnormal cortical ventricular zone morphology ( J:185949 )

• mislocalization of S-phase cells with small ectopic clusters of proliferating cells in the lateral wall of the ventricular zone

decreased neuronal precursor cell number ( J:185949 )

cellular

abnormal neuron differentiation ( J:185949 )

• abnormal neural stem cell polarity

premature neuronal precursor differentiation ( J:185949 )

• premature neurogenesis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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