Phenotypes associated with this allele

• Allele Symbol: Slc9b2^{Gt(D174F03)Wrst}
• Allele Name: gene trap D174F03, German Gene Trap Consortium
• Allele ID: MGI:3892919
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc9b2^Gt(D174F03)Wrst/Slc9b2^Gt(D174F03)Wrst	involves: 129S2/SvPas * C57BL/6	MGI:4818423

Genotype
MGI:4818423

hm1

• Allelic Composition: Slc9b2^{Gt(D174F03)Wrst}/Slc9b2^{Gt(D174F03)Wrst}
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

increased circulating glucose level ( J:197386 )

• increase in serum glucose after i.p. glucose load is greater than for controls

endocrine/exocrine glands

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

skeleton

skeleton phenotype ( J:162142 )

N • bone volume fraction, trabecular number and trabecular thickness normal

N • normal development and function of multinucleated osteoclasts