Slc9b2^{Gt(D174F03)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Slc9b2^{Gt(D174F03)Wrst}
• Name: solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2; gene trap D174F03, German Gene Trap Consortium
• MGI ID: MGI:3892919
• Synonyms: NHA2^gt
• Gene: Slc9b2 Location: Chr3:135013083-135048606 bp, + strand Genetic Position: Chr3, 62.55 cM
• Alliance: Slc9b2^{Gt(D174F03)Wrst} page

Mutation origin

• Mutant Cell Line: D174F03
• Germline Transmission: Earliest citation of germline transmission: J:162142
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rFROSAbgeo+1s
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. A lacZ neo cassette was inserted within intron 1, preceding the start codon within exon 2. RT-PCR showed reduction of transcript in heterozygous and absence in homozygous null mice.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  3SD174F03	ER904998 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr3:135022079-135022416 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  33 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc9b2 Mutation: 42 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)