Phenotypes associated with this allele

• Allele Symbol: Ccdc160^{Gt(179B2)Cmhd}
• Allele Name: gene trap 179B2, Centre for Modeling Human Disease
• Allele ID: MGI:3856076
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Ccdc160^Gt(179B2)Cmhd/Y	chimera involves: 129S1/Sv * 129X1/SvJ	MGI:4456873

Genotype
MGI:4456873

ot1

• Allelic Composition: Ccdc160^{Gt(179B2)Cmhd}/Y
• Genetic Background: chimera involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Ccdc160^{Gt(179B2)Cmhd}/Y chimeras at E9.5 exhibit kinked and open neural tubes and a shortened posterior region

embryo

caudal body truncation ( J:160967 )

♂ • posterior region is shortened at E7.5

abnormal neural tube morphology ( J:160967 )

♂

incomplete rostral neuropore closure ( J:160967 )

♂ • open head

open neural tube ( J:160967 )

♂

kinked neural tube ( J:160967 )

♂ • at E8.5

failure of chorioallantoic fusion ( J:160967 )

♂

nervous system

abnormal neural tube morphology ( J:160967 )

♂

incomplete rostral neuropore closure ( J:160967 )

♂ • open head

open neural tube ( J:160967 )

♂

kinked neural tube ( J:160967 )

♂ • at E8.5

cardiovascular system

delayed heart looping ( J:160967 )

♂ • delayed heart folding at E8.5

♂ • misfolded heart

distended pericardium ( J:160967 )

♂ • some cases of swollen pericardium