Phenotypes associated with this allele

• Allele Symbol: Tg(CAG-Otx2,-EGFP)1Eno
• Allele Name: transgene insertion 1, Eric N Olson
• Allele ID: MGI:3851902
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	H2az2^Tg(Wnt1-cre)11Rth/H2az2^+ Tg(CAG-Otx2,-EGFP)1Eno/?	involves: C3H * C57BL/6	MGI:3851922

Genotype
MGI:3851922

cn1

• Allelic Composition: H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺; Tg(CAG-Otx2,-EGFP)1Eno/?
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:150709 )

• some mice die within 4-6 hours after birth from brain hemorrhaging

cardiovascular system

intracranial hemorrhage ( J:150709 )

• some mice die within 4-6 hours after birth from brain hemorrhaging

• hemorrhaging results from ossification defects in the skull

craniofacial

frontal bone foramen ( J:150709 )

• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone

nervous system

intracranial hemorrhage ( J:150709 )

• some mice die within 4-6 hours after birth from brain hemorrhaging

• hemorrhaging results from ossification defects in the skull

skeleton

frontal bone foramen ( J:150709 )

• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone

failure of intramembranous bone ossification ( J:150709 )

• ossification defects lead to the presence of soft tissues in the frontal and interparietal bone and incomplete skull closure