All Phenotypes Rag1<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rag1^m1Btlr
mutation 1, Bruce Beutler
MGI:3851764

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rag1^m1Btlr/Rag1^m1Btlr	C57BL/6J-Rag1^m1Btlr	MGI:3851765

Allelic Composition	Rag1^m1Btlr/Rag1^m1Btlr
Genetic Background	C57BL/6J-Rag1^m1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1^m1Btlr mutation (1 available); any Rag1 mutation (120 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent late pro-B cells ( J:150635 )

• mice homozygous for this mutation lack peripheral CD19⁺ B220/CD45R⁺ B lymphocytes

• mice homozygous for this mutation exhibit nearly complete deficiency of peripheral CD4⁺ T lymphocytes

• mice homozygous for this mutation exhibit nearly complete deficiency of peripheral CD8⁺ T lymphocytes

immune system

absent late pro-B cells ( J:150635 )

• mice homozygous for this mutation lack peripheral CD19⁺ B220/CD45R⁺ B lymphocytes

• mice homozygous for this mutation exhibit nearly complete deficiency of peripheral CD4⁺ T lymphocytes

• mice homozygous for this mutation exhibit nearly complete deficiency of peripheral CD8⁺ T lymphocytes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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