Phenotypes associated with this allele

• Allele Symbol: Btg3^tm1Tya
• Allele Name: targeted mutation 1, Tadashi Yamamoto
• Allele ID: MGI:3848525
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Btg3^tm1Tya/Btg3^tm1Tya	involves: 129P2/OlaHsd * C57BL/6J	MGI:3848537

Genotype
MGI:3848537

hm1

• Allelic Composition: Btg3^tm1Tya/Btg3^tm1Tya
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Enhanced bone formation after BMP implantation in muscles in Btg3^tm1Tya/Btg3^tm1Tya mice

respiratory system

increased lung tumor incidence ( J:149382 )

• by 21 months, 7.6% of mice develop lung tumors compared to no wild-type mice

increased lung adenoma incidence ( J:149382 )

increased lung carcinoma incidence ( J:149382 )

• alveolar/bronchiolar carcinomas

neoplasm

increased lung tumor incidence ( J:149382 )

• by 21 months, 7.6% of mice develop lung tumors compared to no wild-type mice

increased lung adenoma incidence ( J:149382 )

increased lung carcinoma incidence ( J:149382 )

• alveolar/bronchiolar carcinomas

skeleton

ectopic bone ( J:149251 )

• mice have enhanced formation of bone in skeletal muscle after implantation of gels embedded with bone morphogenetic protein