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| Caption | BTG3 (ANA) deficiency enhances bone formation after BMP (bone morphogenetic protein) implantation in muscles in Btg3tm1Tya/Btg3tm1Tya (KO) mice. A: left panel, shape and size of cholesterol-bearing pullulan cross-linked by poly ethylene glycol (CHP-PEG); right panel, CHP-PEG containing BMP2 was implanted into the quadriceps of the right side (orange arrow) and CHP-PEG-containing vehicle was implanted into the left side (pink arrow). B, x-ray images of newly formed bone after implantation of BMP in CHP-PEG in quadriceps of wild-type (top) and mutant mice (bottom). Orange arrows indicate radiopaque signal of ectopically formed bone induced by BMP. Contralateral side (CHP-PEG with vehicle alone) of either wild-type or mutant mice did not indicate any bone formation. C, three-dimensional bone volume of the ectopically formed bone (ossicle) after implantation in both wild-type and mutant mice. *, p<0.05. | ||||
| Copyright | This image is from Miyai K, J Biol Chem 2009 Apr 17;284(16):10593-600 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:149251 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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