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Allele Symbol Allele Name Allele ID |
Tg(Cdx1-cre)23Kem transgene insertion 23, Rolf Kemler MGI:3841474 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• calcification of the fibrous capsule surrounding the muzzle vibrissae is not observed at 20 weeks of age, however, at one year of age, some calcification is present
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E14.5 embryos consist of a head attached to internal organs including lung, liver and intestine while the urogenital system and mesoderm-derived tissues making up the body wall are highly underdeveloped or absent
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• truncated tail bud region at E9.5
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• truncated tail bud region at E9.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• develop until birth but do not survive
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| N |
• at E9.5 the length of tail buds are similar to controls
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• abnormally folded distally at E9.5
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• at E14.5
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• at E14.5
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• at E14.5
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• small gonads at E14.5
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• deformed shortened forelimb digits vertebrae at E18.5
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• at E18.5
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• at E18.5
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• at E18.5 in rare cases some rudimentary upper hindlimb bones are present
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• at E14.5
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• at E14.5
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• at E18.5
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• deformed shortened fused ribs at E18.5
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• at E18.5
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• at E18.5
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• deformed shortened fused vertebrae at E18.5
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• at E18.5
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• at E18.5
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• at E14.5
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• abnormally folded distally at E9.5
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• at E14.5
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• small gonads at E14.5
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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