Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{tm4(Wnt7a)Amc}
• Allele Name: targeted mutation 4, Andrew P McMahon
• Allele ID: MGI:3831175
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm4(Wnt7a)Amc/? Tg(Nes-cre)1Kln/0	involves: C57BL/6 * SJL	MGI:3831434

Genotype
MGI:3831434

cn1

• Allelic Composition: Gt(ROSA)26Sor^{tm4(Wnt7a)Amc}/?; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vascular endothelial cell morphology ( J:142352 )

• ectopic expression of Wnt7a in the vascular endothelium outside the CNS of E12.5 embryos leads to expression of GLUT-1, a marker normally associated with the blood-brain barrier