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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apctm1Tyj
targeted mutation 1, Tyler Jacks
MGI:3829069
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apctm1Tyj/Apctm1Tyj involves: 129P2/OlaHsd * C57BL/6 MGI:4441382
cn2
 		Apctm1Tyj/Apc+
Tg(Vil1-cre)20Syr/0 		involves: C57BL/6 * DBA/2 MGI:4461182


Genotype
MGI:4441382
hm1
Allelic
Composition		 Apctm1Tyj/Apctm1Tyj
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tyj mutation (1 available); any Apc mutation (151 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:159014 )
• homozygous mice are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities




Genotype
MGI:4461182
cn2
Allelic
Composition		 Apctm1Tyj/Apc+
Tg(Vil1-cre)20Syr/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tyj mutation (1 available); any Apc mutation (151 available)
Tg(Vil1-cre)20Syr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased intestinal adenoma incidence ( J:160399 )
• develop several lesions in the small intestines and colons by 4 - 5 months of age
increased colon adenoma incidence ( J:160399 )
• develop by 4 - 5 months of age

digestive/alimentary system
increased intestinal adenoma incidence ( J:160399 )
• develop several lesions in the small intestines and colons by 4 - 5 months of age
increased colon adenoma incidence ( J:160399 )
• develop by 4 - 5 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory