Phenotypes associated with this allele

• Allele Symbol: M2195Asr
• Allele Name: mutation 2195, Apurva K Srivastava
• Allele ID: MGI:3823083
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	M2195Asr/M2195Asr^+	involves: 129S6/SvEvTac * Black Swiss * C57BL/6J	MGI:3823085
cx2	M2195Asr/M2195Asr^+ Smad2^tm1Cxd/Smad2^+	involves: 129S6/SvEvTac * Black Swiss * C57BL/6J	MGI:3823087

Genotype
MGI:3823085

ht1

• Allelic Composition: M2195Asr/M2195Asr⁺
• Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:141536 )

• originally identified in the Smad2^tm1Cxd/Smad2⁺; however no interaction effect of Smad2^tm1Cxd genotype was observed

skeleton

decreased bone mineral content ( J:141536 )

• low bone mineral content measured by DEXA, as compared to control mice

decreased bone mass ( J:141536 )

• low total bone area as compared to control mice

Genotype
MGI:3823087

cx2

• Allelic Composition: M2195Asr/M2195Asr⁺; Smad2^tm1Cxd/Smad2⁺
• Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C57BL/6J

growth/size/body

decreased body weight ( J:141536 )

• originally identified in the Smad2^tm1Cxd/Smad2⁺; however no interaction effect of Smad2^tm1Cxd genotype was observed

skeleton

decreased bone mineral content ( J:141536 )

• low bone mineral content measured by DEXA, as compared to control mice

decreased bone mass ( J:141536 )

• low total bone area as compared to control mice