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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		M1665Asr
mutation 1665, Apurva K Srivastava
MGI:3823079
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		M1665Asr/M1665Asr+ involves: 129S6/SvEvTac * Black Swiss * C57BL/6J MGI:3823080
cx2
 		M1665Asr/M1665Asr+
Smad2tm1Cxd/Smad2+ 		involves: 129S6/SvEvTac * Black Swiss * C57BL/6J MGI:3823081


Genotype
MGI:3823080
ht1
Allelic
Composition		 M1665Asr/M1665Asr+
Genetic
Background		 involves: 129S6/SvEvTac * Black Swiss * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased lean body mass ( J:141536 )
increased body weight ( J:141536 )
• originally identified in the Smad2tm1Cxd/Smad2+; however no interaction effect of Smad2tm1Cxd genotype was observed

skeleton
increased bone mineral density ( J:141536 )
• higher total body bone density measured by DEXA, as compared to control mice




Genotype
MGI:3823081
cx2
Allelic
Composition		 M1665Asr/M1665Asr+
Smad2tm1Cxd/Smad2+
Genetic
Background		 involves: 129S6/SvEvTac * Black Swiss * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M1665Asr mutation (0 available); any M1665Asr mutation (0 available)
Smad2tm1Cxd mutation (0 available); any Smad2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased lean body mass ( J:141536 )
increased body weight ( J:141536 )
• originally identified in the Smad2tm1Cxd/Smad2+; however no interaction effect of Smad2tm1Cxd genotype was observed

skeleton
increased bone mineral density ( J:141536 )
• higher total body bone density measured by DEXA, as compared to control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory