Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitx2tm1Sac mutation
(0 available);
any
Pitx2 mutation
(38 available)
Pitx2tm2Sac mutation
(0 available);
any
Pitx2 mutation
(38 available)
Tg(Lhb-cre)1Sac mutation
(1 available)
|
|
|
reproductive system
N |
• unlike Pitx2 null mice, mice exhibit normal gonadal development, puberty and fertility
|
growth/size/body
N |
• unlike Pitx2 null mice, growth rates and weights are normal
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargtm2Rev mutation
(1 available);
any
Pparg mutation
(39 available)
Tg(Lhb-cre)1Sac mutation
(1 available)
|
|
|
reproductive system
N |
• both males and females are fertile and produce litters at a normal rate
• estrus patterns are normal
|
|
• diestrus levels of LH are elevated 3-fold
|
homeostasis/metabolism