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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lhx9tm1Dodd
targeted mutation 1 Jane Dodd
MGI:3821769
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Lhx2tm1Dra/Lhx2tm1Dra
Lhx9tm1Dodd/Lhx9tm1Dodd 		Not Specified MGI:3821853
cx2
 		Lhx2tm1Dra/Lhx2+
Lhx9tm1Dodd/Lhx9tm1Dodd 		Not Specified MGI:3821855
cx3
 		Lhx2tm1Dra/Lhx2tm1Dra
Lhx9tm1Dodd/Lhx9+ 		Not Specified MGI:3821856
cx4
 		Lhx2tm1Dra/Lhx2+
Lhx9tm1Dodd/Lhx9tm1Dodd
Robo3tm1Matl/Robo3+ 		Not Specified MGI:3821858


Genotype
MGI:3821853
cx1
Allelic
Composition		 Lhx2tm1Dra/Lhx2tm1Dra
Lhx9tm1Dodd/Lhx9tm1Dodd
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx2tm1Dra mutation (0 available); any Lhx2 mutation (12 available)
Lhx9tm1Dodd mutation (0 available); any Lhx9 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dorsal interneuron 1 morphology ( J:142117 )
• some dl1 neurons migrate ectopically to a more ventral position
• axons (dl1c) fail to cross the midline
• project instead along the ipsilateral ventral funiculus




Genotype
MGI:3821855
cx2
Allelic
Composition		 Lhx2tm1Dra/Lhx2+
Lhx9tm1Dodd/Lhx9tm1Dodd
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx2tm1Dra mutation (0 available); any Lhx2 mutation (12 available)
Lhx9tm1Dodd mutation (0 available); any Lhx9 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dorsal interneuron 1 morphology ( J:142117 )
• a moderate 23% reduction in midline cross over of axons from dl1c neurons




Genotype
MGI:3821856
cx3
Allelic
Composition		 Lhx2tm1Dra/Lhx2tm1Dra
Lhx9tm1Dodd/Lhx9+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx2tm1Dra mutation (0 available); any Lhx2 mutation (12 available)
Lhx9tm1Dodd mutation (0 available); any Lhx9 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dorsal interneuron 1 morphology ( J:142117 )
• a moderate 23% reduction in midline cross over of axons from dl1c neurons




Genotype
MGI:3821858
cx4
Allelic
Composition		 Lhx2tm1Dra/Lhx2+
Lhx9tm1Dodd/Lhx9tm1Dodd
Robo3tm1Matl/Robo3+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx2tm1Dra mutation (0 available); any Lhx2 mutation (12 available)
Lhx9tm1Dodd mutation (0 available); any Lhx9 mutation (31 available)
Robo3tm1Matl mutation (1 available); any Robo3 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dorsal interneuron 1 morphology ( J:142117 )
• a 61% reduction in midline cross over of axons from dl1c neurons




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory