Analysis Tools
immune system
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• serum levels of eosinophils are significantly higher than in wild-type
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• serum levels are significantly higher than in wild-type
• levels of antigen-specific IgE during primary and secondary responses to immunization with TNP-KLH are significantly higher than in controls
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• serum levels are significantly higher than in wild-type
• levels of antigen-specific IgE during primary and secondary responses to immunization with TNP-KLH are marginally higher than in controls
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• mice show greater immediated cutaneous hypersensitivity to antigen challenge indicated by significantly greater footpad swelling after 60 minutes than in controls
• much higher active cutaneous anaphylaxis reaction (swelling) is elicited in flank skin of secondarily immunized mice compared to controls at 30 minutes after TNP-CGG challenge
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• antigen-specific delayed-type hypersensitivity is depressed compared to controls indicated by reduced footpad swelling at 24 hours after immunization with NP OSu
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• after TCR stimulation splenic CD4+ T cells produce less interferon-gamma (Ifng) than wild-type cells at 24 and 96 hours after stimulation
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• after TCR stimulation splenic CD4+ T cells produce significantly more IL4 than wild-type cells at 24 and 96 hours after stimulation
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• after TCR stimulation splenic CD4+ T cells produce significantly more IL5 than wild-type cells at 24 and 96 hours after stimulation
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hematopoietic system
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• serum levels of eosinophils are significantly higher than in wild-type
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• serum levels are significantly higher than in wild-type
• levels of antigen-specific IgE during primary and secondary responses to immunization with TNP-KLH are significantly higher than in controls
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• serum levels are significantly higher than in wild-type
• levels of antigen-specific IgE during primary and secondary responses to immunization with TNP-KLH are marginally higher than in controls
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