Phenotypes associated with this allele

• Allele Symbol: Bdnf^tm1Meg
• Allele Name: targeted mutation 1, Micheal E Greenberg
• Allele ID: MGI:3809491
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bdnf^tm1Meg/Bdnf^tm1Meg	Not Specified	MGI:3809495

Genotype
MGI:3809495

hm1

• Allelic Composition: Bdnf^tm1Meg/Bdnf^tm1Meg
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal axon pruning ( J:139381 )

• sympathetic neurons of the superior cervical ganglion (SCG) have improper pruning of axons from neurons that reach into both eye compartments

• by 50 days of age, wild-type mice prune axons from SCG so that only 36% of SCG neurons reach into both eyes

• mutant mice have less axon pruning, which leads to 51% of SCG neurons projecting into both eyes at 50 days of age

cellular

abnormal axon pruning ( J:139381 )

• sympathetic neurons of the superior cervical ganglion (SCG) have improper pruning of axons from neurons that reach into both eye compartments

• by 50 days of age, wild-type mice prune axons from SCG so that only 36% of SCG neurons reach into both eyes

• mutant mice have less axon pruning, which leads to 51% of SCG neurons projecting into both eyes at 50 days of age